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Chronic disease treatment syringes

BD Neopak™ Glass Prefillable Syringe (PFS) platform and Integrated Drug Delivery

Committed to drug delivery excellence

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Overview

The BD Neopak™ Glass Prefillable Syringe platform with tailorable medication delivery solution can help support the development of your biologic drug.

Getting your drug to market with a solution focused on patient safety and usability

Our diverse portfolio features devices and systems that can deliver biologics across a wide range of volumes and viscosities, helping to treat patients with chronic conditions.

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Features and Benefits

Various configurations

  • Available in 1ml and 2.25 ml configurations
  • Designed to enhance patient experience when administering high viscosity/high volume drugs 2,3
  • Shorter 8mm needle
  • Thinner wall cannula technology

Positive patient acceptance

  • May help reduce the risk of intramuscular injection2
  • Decreased injection force and/or time at a fixed solution viscosity3
  • Reduced needle related anxiety2
  • Positive impact on patient acceptance2

Enhanced particle reduction with immobilized silicone coating

  • Designed to stabilise the silicone lubricant layer without introducing new chemistry4,5*
  • Enhanced particle reduction with immobilised silicone coating

Compatibility with sensitive biopharmaceuticals

  • Minimizing sub-visible particle generation to help meet compliance standards for particulates4,5,6
  • Stabilised silicone lubricant layer and mechanical properties to aid in full drug
  • delivery4,5,6,7
  • Maintained gliding and activation performance over time, as compared to
  • conventional silicone5

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Footnotes

*XSi does not introduce new chemical substances or molecule entity and only modifies the distribution of chemical functions which already exists in PDMS (Polydimethylsiloxane) silicone

** USP 788 standard

References

  1. World Preview 2018, Outlook to 2024. Evaluate Pharma, 2018
  2. User experience for manual injection of 2 mL viscous solutions is enhanced by a new prefillable syringe with a stacked 8 mm ultra-thin wall needle, Expert Opinion on Drug Delivery, Pager 2020
  3. Injection time and ejection force calculation, BD internal study, 2020
  4. Depazet al. Cross-Linked Silicone Coating: A Novel Prefilled Syringe Technology That Reduces Subvisible Particles and Maintains Compatibility with Biologics. JOURNAL OF PHARMACEUTICAL SCIENCES 103:1384–1393, 2014
  5. BD Neopak™ XSi™ 1mlL-Competitive Benchmark [Internal Study]. Pont-de-Claix, FR: Becton Dickinson and Company; 2020
  6. BD Neopak™ XSi™ 2.25ml 27G STW ½’’ - Empty AGF. [internal Study].Pont-de-Claix, FR: Becton Dickinson and Company. 2019
  7. BD Neopak™ XSi™ 2.25ml 27G STW ½’’ - injection time. [internal Study]. Pont-de-Claix, FR: Becton Dickinson and Company. 2019
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