Arista™ AH 3g

Arista^TM  AH is an absorbable powdered hemostatic agent intended for application to surgical wound sites to control bleeding. It is a fine, dry, sterilized white powder that is biocompatible, non-pyrogenic, and typically absorbed within 24-48 hours. 

Arista™ AH is a 100% plant based absorbable surgical hemostatic powder derived from purified plant starch. The power of Arista™ AH lies in its Microporous Polysaccharide Hemospheres, a patented blood clotting technology. Consisting of microporous particles with a controlled pore size, the spheres are designed to act as a molecular sieve. The powerful osmotic action dehydrates and gels the blood on contact to accelerate the natural clotting process.

The best tools for blood clotting include hemostatic agents, thrombolytics, and anticoagulant medications. 

In surgery, primary hemostasis techniques include removing all excess blood, applying the hemostat to the wound site, and adding pressure to the wound until hemostasis occurs.

Blood clot powder acts as a mechanical barrier to bleeding and provides a matrix that facilitates clotting alongside biological agents that catalyze coagulation in order to achieve hemostasis.

BD’s hemostatic powder is made of purified plant starch and microporous polysaccharide hemospheres. 

A topical powder is a type of hemostat that is used for direct application to the wound site, helping to facilitate hemostasis by acting as a mechanical barrier.

While blood does coagulate naturally, according to a publication the best way to facilitate blood coagulation where traditional methods are no longer efficient is to use hemostatic agents.

In clinical trials, Arista™ AH MPH hemostatic powder was found to significantly reduce the rate of overall post-procedural complications including pocket hematoma and infection.

Surgical hemostasis is the act of stopping the free flow of blood from injury sites through blood coagulation. Typically, surgical hemostasis will involve hemostatic agents to facilitate blood coagulation. 

Methods of surgical hemostasis include mechanical methods like gauze, sponges, or powder, thermal-based methods such as electrosurgery, and chemical methods such as pharmacological agents. 

1. Blot, wipe, or suction the bleeding tissue. It is important to remove excess blood so Arista™ AH may be applied immediately and directly to the site of active bleeding.

2. Position the applicator tip as close to the source of bleeding as possible. Immediately apply a liberal amount of Arista™ AH at the site of bleeding within the wound, to completely cover the wound. Deep wounds may require equally deep application of Arista™ AH. To minimize occlusion of the tip, pressure should be applied to deliver Arista™ AH as the applicator enters the wound

3. Quickly apply wound-appropriate, direct pressure over the treated site. Use of a non-adhering substrate to apply pressure may prevent adhesion of the formed clot to the surgical glove or other instrumentation. Amount and duration of pressure is wound dependent. For oozing, pressure may not be necessary. For more profusely bleeding wounds, pressure should be maintained longer.

4. If bleeding or oozing continues, remove excess Arista™ AH and reapply.

5. If any material other than the clot-bound Arista™  AH  (i.e. surgical dressing) adheres to the wound site, irrigate the material with saline and carefully remove it from the treated site.

6. Immediately upon contact with blood or fluid, Arista™ AH will swell to approximately 5 times its original volume. Once hemostasis is achieved, excess Arista™ AH should be carefully removed by irrigation and aspiration. Avoid irrigation of direct suction of the formed blood clot.

Apply a liberal amount of Arista™ AH to the bleeding site followed by pressure until hemostasis is achieved.  After hemostasis is achieved, remove Arista™  AH  by irrigation and/or aspiration.

Examples of surgeries that Arista™ AH can be used in include:

• Cardiothoracic and cardiovascular
• Vascular
• Gynecological
• Urology
• Orthopedic surgery
• General surgery
• Plastic surgery
• Ear
• Nose
• Throat (ENT) surgery

Simple to Use

• Ready on demand
• Simply pop the cap and apply the powder directly to the bleeding site
• No mixing and no refrigeration
• Five-year shelf life

Safe and Thrombin-Free

• Synthesized from a purified plant starch
• Thrombin-free, biocompatible and nonpyrogenic
• Typically absorbed and cleared within 24–48 hours by amylases
• Arista™ AH is the only currently available hemostat that is approved for cell salvage compatibility

Effective Hemostat

• The clotting process begins on contact, regardless of patient’s coagulation status
• Complete hemostasis can be achieved in minutes
• Provides broad area coverage