ChloraPrep® patient preoperative skin preparation products

Choose the skin antiseptic with a unique formulation, hands-free applicator and proven efficacy that can help standardize care across procedures


ChloraPrep® products help reduce bacteria on the skin that can cause infection.

The proven 2% chlorhexidine gluconate (CHG) and 70% isopropyl alcohol (IPA) formulation has:

  • Shown to outperform iodine-based products for preoperative skin antisepsis.1,2,3
  • Appeared in Level I evidence-based studies.
  • Appeared in more than 20 peer-reviewed publications.

Active ingredients

  • IPA, which denatures cell proteins to rapidly kill microorganisms.
  • CHG, which disrupts the cell membrane and precipitating cell contents to maintain persistent antimicrobial activity.

Patented applicator
The applicator promotes aseptic technique and reduces direct patient contact, helping decrease the risk of cross-contamination.

1 Saltzman M, Nuber G, Gryzlo S, et. al. Efficacy of surgical preparation solutions in shoulder surgery. J Bone Joint Surg Am. 2009;91(8):1949-1953.

2 Adler M, Brigger K, Bishop K, et al. Comparison of bactericidal properties of alcohol-based chlorhexidine versus povidone-iodine prior to amniocentesis. Am J Perinatol. 2012;29(6):455-458.

3 Ostrander R, Bott M, Brage M. Efficacy of surgical preparation solutions in foot and ankle surgery. J Bone Joint Surg Am. 2005;87(5):980-985.


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